14581-85-2

Upstream product

• 88-75-5 2-hydroxynitrobenzene 
• 572-09-8 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide 
• 604-69-3 β-D-glucose pentaacetate 
• 604-68-2 α-D-glucopyranose peracetylate 
• 6919-96-6 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide 

Downstream Products

• 2816-24-2 2-nitrophenyl β-D-glucopyranoside 
• 7265-01-2 2-aminophenyl β-D-glucopyranoside 

Relevant academic research and scientific papers

Crystal structure and solid state 13C NMR analysis of nitrophenyl 2,3,4,6-tetra-O-acetyl-β-D-gluco- and D-galactopyranosides

The X-ray diffraction analysis of o-nitrophenyl 2,3,4,6-tetra-O-acetyl- β-d-galactopyranoside (1), m-nitrophenyl 2,3,4,6-tetra-O-acetyl-β-d- galactopyranoside, p-nitrophenyl 2,3,4,6-tetra-O-acetyl-β-d- galactopyranoside and o-nitrophenyl 2,3,4,6-tetra-O-a

Enhancing cellular sulfane sulfur through β-glycosidase-activated persulfide donors: mechanistic insights and oxidative stress mitigation

Sulfane sulfur species such as persulfides and polysulfides along with hydrogen sulfide protect cells from oxidative stress and are key members of the cellular antioxidant pool. Here, we report perthiocarbamate-based prodrugs that are cleaved by β-glycosidases to produce persulfide and relatively innocuous byproducts. The β-glucosidase-activated persulfide donor enhances cellular sulfane sulfur and protects cells against lethality induced by elevated reactive oxygen species (ROS).

Application of halide molten salts as novel reaction media for O-glycosidic bond formation

In this study we have explored the application of halide molten salts as reaction media for O-glycosidic bond formation under basic conditions and mild heating. Eighteen different room-temperature ionic liquids and molten salts, representing four different classes of cations (i.e. imidazolium, pyridinium, pyrrolidinium and ammonium), were screened in the glycosidation reaction of p-nitrophenol with aceto-bromo-α-D-galactose. 1-Butyl-4-methylimidazolium chloride (BMIM·Cl) gave the best results and was applied in the reactions of other phenolic substrates to give the products with up to 80% yields. All the reactions were highly selective to give the β-anomers, and the molten salt BMIM·Cl could easily be reused with no apparent loss in activity.

Total synthesis of α-deamino-3-(β-D-glucopyranosyloxy)kynurenine

α-Deamino-3-β-glucopyranosyloxy)kynurenine, a yellow, fluorescent compound isolated from human lens, was synthesized in 8 steps (10% overall yield) from commercially available 3-methoxy-2-nitrobenzaldehyde. Key events included preparation and glucosylatio

Preparative Bioorganic Chemistry, XVI. Synthesis of 3,4'-Dihydroxypropiophenone 3-&β-D-Glucopyranoside, a Constituent of Betula platyphylla var. japonica, by Enzymatic Transglucosylation

3,4'-Dihydroxypropiophenone 3-β-D-glucopyranoside (1a) has been synthesized, without having recourse to any protective group technology, by transglucosylation catalyzed by lactase from Kluyveromyces lactis. Key words: Antifeedant; Betula platyphylla; β-D-glucopyranoside; lactase; transglucosylation.