145822-90-8

Basic information

• Product Name: Ethyl (3-oxocyclobutyl)acetate
• Synonyms: cyclobutaneacetic acid, 3-oxo-, ethyl ester
• CAS NO: 145822-90-8
• Molecular Formula: C₈H₁₂O₃
• Molecular Weight: 156.1791
• Mol File: 145822-90-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 224.554°C at 760 mmHg
• Flash Point: 91.281°C
• Density: 1.103g/cm³
• Vapor Pressure: 0.091mmHg at 25°C
• Refractive Index: 1.462
• CAS DataBase Reference: Ethyl (3-oxocyclobutyl)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl (3-oxocyclobutyl)acetate(145822-90-8)
• EPA Substance Registry System: Ethyl (3-oxocyclobutyl)acetate(145822-90-8)

Safety Data

• Hazardous Substances Data: 145822-90-8(Hazardous Substances Data)

Upstream product

• 145822-87-3 (Z)-6-Bromo-5,5-diethoxy-hex-2-enoic acid ethyl ester 
• 145822-89-5 (3,3-Diethoxy-cyclobutyl)-acetic acid ethyl ester 

Relevant articles and documents

Easy preparation of a cyclobutanone ketal via a radical cyclization. The gem-dialkoxy effect

A new method for the facile synthesis of cyclobutanones, the key step of which is a radical cyclization to generate the four-membered ring, is reported. In addition, a comparison of the gem-dialkyl and gem-dialkoxy effects in radical cyclizations to give cyclobutane systems shows that in this system the gem-dialkoxy effect is larger.