145822-96-4

Upstream product

• 159812-22-3 C₄₂H₄₈O₈ 
• 159812-20-1 Bis-[(4S,6S)-6-(2-benzyloxy-ethyl)-2,2-dimethyl-[1,3]dioxan-4-yl]-methanone 
• 159812-21-2 C₃₂H₄₄O₆ 
• 127760-85-4 (S)-5-Benzyloxy-3-(tetrahydro-pyran-2-yloxy)-pentanal 

Downstream Products

• 145823-00-3 (4R,6S)-4-Hydroxy-6-{(1R,2S)-2-methoxy-3-[(2S,4S)-2-(4-methoxy-phenyl)-[1,3]dioxan-4-yl]-1-methyl-propyl}-tetrahydro-pyran-2-one 
• 159812-23-4 (3S,4R,6S)-4-Hydroxy-6-{(1R,2S)-2-methoxy-3-[(2S,4S)-2-(4-methoxy-phenyl)-[1,3]dioxan-4-yl]-1-methyl-propyl}-3-methyl-tetrahydro-pyran-2-one 
• 159692-46-3 (4R,5S)-3-[(2R,3S,4R)-3-Hydroxy-4-((4R,6S)-6-{(1R,2S)-2-methoxy-3-[(2S,4S)-2-(4-methoxy-phenyl)-[1,3]dioxan-4-yl]-1-methyl-propyl}-2,2-dimethyl-[1,3]dioxan-4-yl)-2-methyl-pentanoyl]-4-methyl-5-phenyl-oxazolidin-2-one 
• 145822-97-5 (2S,4S,6S)-4-(2-Benzyloxy-ethyl)-6-[(1R,2S,4S)-6-benzyloxy-2-methoxy-4-(4-methoxy-benzyloxy)-1-methyl-hexyl]-2-(4-methoxy-phenyl)-[1,3]dioxane 

Relevant academic research and scientific papers

Synthetic Study of Marine Macrolide Swinholide A. Stereocontrolled Synthesis of the C11-C23 Segment

The C11-C23 segment 4 of swinholide A (1) was synthesized stereoselectively starting from (S)-malic acid via double nitroaldol reaction under high pressure and differentiation of the left and right parts of the symmetric compound 10 as the key steps.