145842-46-2Relevant articles and documents
Lipase-catalysed Enantioselective Acylation of N-Protected or Unprotected 2-Aminoalkan-1-ols
Fernandez, Susana,Brieva, Rosario,Rebolledo, Francisca,Gotor, Vicente
, p. 2885 - 2890 (2007/10/02)
Porcine pancreatic lipase (PPL) catalysed the acylation of 2-aminoalkan-1-ols; the enantiospecificity depends on the starting amino alcohol.The catalytic activity of the enzyme was markedly improved when the benzyl carbamate derivatives were used as substrates; in general, the enzyme displayed a high enantiospecificity.