145843-75-0Relevant academic research and scientific papers
The preparation of intermediates for the synthesis of 1D-myo-inositol 1,4,5- and 2,4,5-trisphosphates, 1,4-bisphosphate 5-phosphorothioate, and 4,5-bisphosphate 1-phosphorothioate from 1D-3,6-di-O-benzyl-1,2-O-isopropylidene-myo-inositol
Desai,Gigg,Gigg,Martin-Zamora
, p. 59 - 77 (2007/10/02)
The preparation of 1D-1,6-di-O-benzyl-2,5-di-O-p-methoxybenzyl-myo-inositol is described. This compound and 1D-3,6-di-O-benzyl-1,2-O-isopropylidene-myo-inositol were converted into 1D-1,3,6-tri-O-benzyl-myo-inositol which was phosphorylated to give an int
Total Synthesis of the Second Messenger Analogue D-myo-Inositol 1- Phosphorothioate 4,5-Biphosphate: Optical Resolution of DL-1-O-Allyl-2,3,6-tri-O-Benzyl-myo-inositol and Fluorescent Labelling of myo-Inositol 1,4,5-Triphposphate
Lampe, Dethard,Mills, Stephen J.,Potter, Barry V. L.
, p. 2899 - 2906 (2007/10/02)
Two routes for the synthesis of the myo-inositol 1,4,5-triphosphate analogue myo-inositol 1-phosphorothioate 4,5-bisphosphate have been devised.DL-2,3,6-Tri-O-benzyl-1-O-(cis-prop-1-enyl)-myo-inositol was prepared from DL-1-O-allyl-2,3,6-tri-O-benzyl-myo-
The preparation of intermediates for the synthesis of 1D-myo-inositol 1,4,5-triphosphate, a second messenger for signal transduction in cells
Desai, Trupti,Gigg, Jill,Gigg, Roy,Payne, Sheila,Penades, Soledad
, p. 1 - 22 (2007/10/02)
Racemic 1,2,4-tri-O-benzyl-5,6-O-isopropylidene-myo-inositol was prepared by a new route involving crotyl (but-2-enyl) ethers and converted into (-)-ω-camphanates to give the pure crystalline 1L-diastereoisomer and the chirally impure, syrupy 1D-diastereo
Synthesis of myo-Inositol 1-Phosphorothioate 4,5-Bisphosphate: Preparation of a Fluorescently Labelled myo-Inositol 1,4,5-Trisphosphate Analogue
Lampe, Dethard,Potter, Barry V. L.
, p. 1500 - 1501 (2007/10/02)
Synthesis of myo-inositol 1-phosphorothioate 4,5-bisphosphate, a novel analogue of the second messenger myo-inositol 1,4,5-trisphosphate allows, for the first time, the attachment of a fluorescent reporter group at the 1-position.
