145850-48-2Relevant academic research and scientific papers
Solvent-Dependent Reversible Rearrangement of 4-(Hydroxyimino)hexahydropyrimidines to 4-Aminotetrahydropyrimidine 3-Oxides
Korbonits, Dezsoe,Tobias-Heja, Erzsebet,Simon, Kalman,Kolonits, Pal
, p. 19 - 22 (2007/10/02)
1,2-Disubstituted 4-hydroxyiminohexahydropyrimidines (8) isomerize in alcohols to yield 1,2-disubstituted 4-aminotetrahydropyrimidine 3-oxides (9).In aprotic solvents the opposite transformation (9-->8) takes place, presumably by a different mechanism.The
Synthesis of 4-Aminopyrimidines from 1,2,4-Oxadiazoles. Part 4. A Novel Heterocyclic Rearrangement: Formation of 4-Hydroximinohexahydropyrimidines from 3-(2-Aminoethyl)-4,5-dihydro-1,2,4-oxadiazoles
Korbonits, Dezsoe,Tobias-Heja, Erzsebet,Simon, Kalman,Kramer, Gyoergy,Kolonits, Pal
, p. 3069 - 3074 (2007/10/02)
The 4,5-dihydro derivatives of 3-(2-aminoethyl)-5-substituted-1,2,4-oxadiazoles 1 have been prepared.These derivatives 8a-d rearrange readily, but in contrast to compounds 1, not to pyrazoles, but to 2-aryl-1-benzyl-4-hydroximinohexahydropyrimidines 9a-d.
