145858-50-0

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Basic information

Product Name: 5-[(3-CHLOROPHENYL)-1H-IMIDAZOL-1-YLMETHYL]-1H-BENZIMIDAZOLE HYDROCHLORIDE
Synonyms: 5-[(3-CHLOROPHENYL)-1H-IMIDAZOL-1-YLMETHYL]-1H-BENZIMIDAZOLE HYDROCHLORIDE;LIAROZOLE HYDROCHLORIDE
CAS NO:145858-50-0
Molecular Formula: C17H14Cl2N4
Molecular Weight: 345.2259
EINECS: N/A
Product Categories: N/A
Mol File: 145858-50-0.mol
Article Data: 0

Chemical Properties

Melting Point: N/A
Boiling Point: 578.2°Cat760mmHg
Flash Point: 303.5°C
Appearance: /
Density: g/cm³
Refractive Index: N/A
Storage Temp.: Store at +4°C
Solubility: N/A
CAS DataBase Reference: 5-[(3-CHLOROPHENYL)-1H-IMIDAZOL-1-YLMETHYL]-1H-BENZIMIDAZOLE HYDROCHLORIDE(CAS DataBase Reference)
NIST Chemistry Reference: 5-[(3-CHLOROPHENYL)-1H-IMIDAZOL-1-YLMETHYL]-1H-BENZIMIDAZOLE HYDROCHLORIDE(145858-50-0)
EPA Substance Registry System: 5-[(3-CHLOROPHENYL)-1H-IMIDAZOL-1-YLMETHYL]-1H-BENZIMIDAZOLE HYDROCHLORIDE(145858-50-0)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 145858-50-0(Hazardous Substances Data)

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145858-50-0 Usage

Uses

Different sources of media describe the Uses of 145858-50-0 differently. You can refer to the following data:
1. Antineoplastic.
2. Liarozole Hydrochloride is a Imidazole-containing compound that inhibits the cytochrome P450-dependent metabolism.

Biological Activity

Cytochrome P450 inhibitor. Inhibits several cytochrome P450 enzymes including aromatase (CYP19) and retinoic acid 4-hydroxylase (CYP26). Blocks retinoic acid metabolism (retinoic acid metabolism blocking agent, RAMBA). Displays antitumor activity against androgen-dependent and independent rat prostate carcinomas.

Check Digit Verification of cas no

The CAS Registry Mumber 145858-50-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,5,8,5 and 8 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 145858-50:
(8*1)+(7*4)+(6*5)+(5*8)+(4*5)+(3*8)+(2*5)+(1*0)=160
160 % 10 = 0
So 145858-50-0 is a valid CAS Registry Number.

145858-50-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name	Liarozole hydrochloride,5-[(3-Chlorophenyl)-1H-imidazol-1-ylmethyl]-1H-benzimidazolehydrochloride

1.2 Other means of identification

Product number	-
Other names	LIAROZOLE HYDROCHLORIDE

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:145858-50-0 SDS

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