1458630-39-1

Basic information

• Product Name: C₁₂H₁₃BrClN₃
• Synonyms: C₁₂H₁₃BrClN₃
• CAS NO: 1458630-39-1
• Molecular Weight: 314.612
• Mol File: 1458630-39-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₂H₁₃BrClN₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₂H₁₃BrClN₃(1458630-39-1)
• EPA Substance Registry System: C₁₂H₁₃BrClN₃(1458630-39-1)

Safety Data

• Hazardous Substances Data: 1458630-39-1(Hazardous Substances Data)

Upstream product

• 766-96-1 4-bromo-1-ethynylbenzene 
• 671821-46-8 1-azido-4-chloro-butane 

Downstream Products

• 1458630-51-7 C₂₃H₂₈BrN₅O 

Relevant articles and documents

Synthesis and binding affinity of new 1,4-disubstituted triazoles as potential dopamine D3 receptor ligands

A series of new 1,4-disubstituted triazoles was prepared from appropriate arylacetylenes and aminoalkylazides using click chemistry methodology. These compounds were evaluated as potential ligands on several subtypes of dopamine receptors in in vitro competition assays, showing high affinity for dopamine D3 receptors, lower affinity for D2 and D4, and no affinity for the D1 receptors. Compound 18 displayed the highest affinity at the D3 receptor with a Ki value of 2.7 nM, selectivity over D2 (70-fold) and D4 (200-fold), and behaviour as a competitive antagonist in the low nanomolar range.