145901-58-2

Usage

General Description

1,2-Ethanediamine, N-(triphenylmethyl)-N'-[2-[(triphenylmethyl)amino]ethyl]- is a chemical compound with the molecular formula C38H42N2. It consists of two amine groups and a triphenylmethyl group, and is used in organic chemistry as a reagent for the selective protection of the amino group of amino acids. It is also used in the synthesis of various pharmaceuticals and other organic compounds. This chemical is a white to light yellow crystalline powder with a molecular weight of 526.76 g/mol and is soluble in organic solvents such as methanol and ethanol.

Upstream product

• 76-83-5 trityl chloride 
• 111-40-0 3-azapentane-1,5-diamine 

Downstream Products

• 593280-08-1 4-{bis-[2-(trityl-amino)-ethyl]-carbamoyl}-butyric acid methyl ester 

Relevant academic research and scientific papers

Rapid oligosaccharide synthesis on a fluorous support

The novel fluorous support Hfb (hexakisfluorous chain-type butanoyl) was easily prepared. The Hfb group was readily introduced into the anomeric hydroxyl group of a carbohydrate, and was recyclable after cleavage. The use of the Hfb group was applicable for the rapid oligosaccharide synthesis in which the synthetic intermediates could be purified using fluorous and normal organic solvents. Each synthetic intermediate could be monitored by TLC, NMR and mass spectrometry. Graphical Abstract

Synthesis of hexamine ligands by using trityl as an N-blocking group

The amino-groups of diethylenetriamine were regioselectively protected by trityl groups and then reacted with dihalogenated alkylane to give the terminal N-blocked hexamine derivatives, from which a series of hexamine ligands (5(a-f)) were obtained by rem

Oligosaccharide synthesis on a fluorous support

The fluorous support Hfb (see picture) enabled high-yielding oligosaccharide syntheses in which the synthetic intermediates could be purified by simple fluorous-organic solvent extraction, and the reactions could be monitored spectroscopically and by TLC.

TARGETED RADIOPHARMACEUTICALS FOR THE DIAGNOSIS AND TREATMENT OF PROSTATE CANCER

A compound of general formula (I): wherein: n is 1, 2 or 3; R1, R2, R3 and R4, independently represent OH or Q; and 20 Q represents a tissue-targeting moeity selected from the group consisting of or a stereoisomer, a hydrate, a solvate, or a salt thereof, or a mixture of same, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said 25 compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of soft tissue diseases, as a sole agent or in combination with other active ingredients.