145913-80-0 Usage
General Description
[(2R,5S)-5-(6-amino-2-fluoro-9H-purin-9-yl)-1,3-oxathiolan-2-yl]methanol is a chemical compound with a complex molecular structure. It contains a purine ring, a fluorine atom, and a thiol group, among other functional groups. The compound also includes a methanol molecule attached to the oxathiolan ring. This chemical is likely to have pharmaceutical or biological applications, as it contains a purine derivative, which is a common structural motif in many drugs and natural products. The presence of the fluorine atom may also impart unique properties to the compound, such as increased stability or altered reactivity. The compound's stereochemistry, indicated by the (2R,5S) prefix, further adds to its potential pharmaceutical relevance, as stereochemistry can greatly impact the biological activity of a molecule.
Check Digit Verification of cas no
The CAS Registry Mumber 145913-80-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,5,9,1 and 3 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 145913-80:
(8*1)+(7*4)+(6*5)+(5*9)+(4*1)+(3*3)+(2*8)+(1*0)=140
140 % 10 = 0
So 145913-80-0 is a valid CAS Registry Number.
145913-80-0Relevant articles and documents
Structure-Activity Relationships of β-D-(2S,5R)- and α-D-(2S,5S)-1,3-oxathiolanyl Nucleosides as Potential Anti-HIV Agents
Jeong, Lak S.,Schinazi, Raymond F.,Beach, J. Warren,Kim, Hea O.,Shanmuganathan, Kirupathevy,et al.
, p. 2627 - 2638 (2007/10/02)
The β-D-(2S,5R)- and α-D-(2S,5S)-1,3-oxathiolanylpyrimidine and -purine nucleosides with natural nucleoside configuration were synthesized and evaluated against HIV-1 in human peripheral blood mononuclear (PBM) cells.The key intermediate 14, which was uti
