1459835-06-3

Upstream product

• 1459834-83-3 C₁₄H₁₉NO₄ 
• 162255-08-5 (2S,3S)-4-(benzyloxy)-3-hydroxy-N-methoxy-N,2-dimethylbutanamide 
• 1459835-03-0 (4R,5S)-6-(benzyloxy)-5-(tert-butyldimethylsilyloxy)-4-methylhexan-1-ol 
• 179945-15-4 (4R,5S,E)-ethyl 6-(benzyloxy)-5-(tert-butyldimethylsilyloxy)-4-methylhex-2-enoate 
• 157220-45-6 <2S,3S>-3-<<<(1,1-dimethylethyl)dimethylsilyl>oxy>-N-methoxy>-N,2-dimethyl-4-phenylmethoxybutanamide 
• 1030268-21-3 trimethylsulfonium iodide 
• 1459835-04-1 ((2S,3R)-1-(benzyloxy)-3-methyl-4-((R)-oxiran-2-yl)butan-2-yloxy)-(tert-butyl)dimethylsilane 
• 162255-09-6 <2S,3S>-3-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-2-methyl-4-(phenylmethoxy)butanal 

Downstream Products

• 1459835-07-4 (2S,3R,5R)-1-(benzyloxy)-3-methylhept-6-ene-2,5-diol 
• 1459835-08-5 (2S,3R,5R,6S)-6-((benzyloxy)methyl)tetrahydro-2-(iodomethyl)-5-methyl-2H-pyran-3-ol 
• 1459835-09-6 (2R,3R,5R,6S)-2-(azidomethyl)-6-(benzyloxymethyl)-5-methyltetrahydro-2H-pyran-3-ol 
• 1459835-10-9 ((2R,3R,5R,6S)-2-(azidomethyl)-6-(benzyloxymethyl)-5-methyltetrahydro-2H-pyran-3-yloxy)(tert-butyl)dimethylsilane 
• 1459835-18-7 ((2S,3R,5R,6S)-6-((benzyloxy)methyl)tetrahydro-2-(iodomethyl)-5-methyl-2H-pyran-3-yloxy)(tert-butyl)dimethylsilane 
• 1459835-19-8 ((3R,5R,6S)-6-((benzyloxy)methyl)tetrahydro-5-methyl-2-methylene-2H-pyran-3-yloxy)(tert-butyl)dimethylsilane 
• 1459835-20-1 ((2S,3R,5R,6S)-6-(benzyloxymethyl)-3-(tert-butyldimethylsilyloxy)-5-methyltetrahydro-2H-pyran-2-yl)methanol 
• 1459835-21-2 ((2R,3R,5R,6S)-2-(azidomethyl)-6-((benzyloxy)methyl)tetrahydro-5-methyl-2H-pyran-3-yloxy)(tert-butyl)dimethylsilane 

Relevant academic research and scientific papers

Enantioselective synthesis of δ-/γ-alkoxy-β-hydroxy- α-alkyl-substituted Weinreb amides via DKR-ATH: Application to the synthesis of advanced intermediate of (-)-brevisamide

A method of preparing stereodefined δ-/γ-alkoxy-β-hydroxy- α-alkyl-substituted Weinreb amides containing two successive hydroxyl-alkyl stereocenters has been developed. Further, this strategy coupled with organo-catalyzed asymmetric epoxidation culminates in the synthesis of a critical intermediate of (-)-brevisamide and its diastereomers.