146006-63-5

Upstream product

• 71432-55-8 2-tert-butyl-1,3-diisopropylisourea 
• 146006-47-5 (1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-6-phenyl-hexyl)-6-((E)-(4S,6S)-4,6-dimethyl-oct-2-enoyloxy)-4,7-dihydroxy-2,8-dioxa-bicyclo[3.2.1]octane-3,4,5-tricarboxylic acid 3-benzyl ester 
• 100-51-6 benzyl alcohol 
• 138682-84-5 zaragozic acid A 

Downstream Products

• 154110-05-1 C₅₄H₇₆O₁₅ 
• 146968-25-4 (1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-6-phenyl-hexyl)-6-((E)-(4S,6S)-4,6-dimethyl-oct-2-enoyloxy)-4-hydroxy-7-(1-methoxy-1-methyl-ethoxy)-2,8-dioxa-bicyclo[3.2.1]octane-3,4,5-tricarboxylic acid 4,5-di-tert-butyl ester 
• 154110-06-2 (1S,3R,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-6-phenyl-hexyl)-6-((E)-(4S,6S)-4,6-dimethyl-oct-2-enoyloxy)-4-hydroxy-3-hydroxymethyl-7-(1-methoxy-1-methyl-ethoxy)-2,8-dioxa-bicyclo[3.2.1]octane-4,5-dicarboxylic acid di-tert-butyl ester 
• 154110-09-5 (1S,3R,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-6-phenyl-hexyl)-6-((E)-(4S,6S)-4,6-dimethyl-oct-2-enoyloxy)-4,7-dihydroxy-3-methyl-2,8-dioxa-bicyclo[3.2.1]octane-4,5-dicarboxylic acid di-tert-butyl ester 
• 154110-10-8 C₃-methyl, C₃-decarboxy-zaragozic acid A 

Relevant academic research and scientific papers

The Synthesis of C3-Methyl, C3-Decarboxy-Zaragozic Acid A. A Potent Squalene Synthase Inhibitor

The title compound and its C4-pivaloyloxy methyl (POM) ester have been synthesized by converting zaragozic acid A to the key intermediate of the protected C3-hydroxymethyl compound 6.Subsequent radical deoxygenation via the Barton-McCombie procedure, foll