146012-94-4Relevant academic research and scientific papers
Room-Temperature Direct β-Arylation of Thiophenes and Benzo[b]thiophenes and Kinetic Evidence for a Heck-type Pathway
Colletto, Chiara,Islam, Saidul,Juliá-Hernández, Francisco,Larrosa, Igor
supporting information, p. 1677 - 1683 (2016/02/20)
The first example of a regioselective β-arylation of benzo[b]thiophenes and thiophenes at room temperature with aryl iodides as coupling partners is reported. This methodology stands out for its operational simplicity: no prefunctionalization of either st
Investigation of bioisosters of the growth hormone secretagogue L-692,429
Ankersen, Michael,Peschke, Bernd,Hansen, Birgit Sehested,Hansen, Thomas Kruse
, p. 1293 - 1298 (2007/10/03)
The synthesis and structure-activity relationships of several analogs of L-692,429 with modifications in the biaryl and tetrazole moieties are described and several derivatives were found to be equipotent or slightly more potent than L-692,429.
