146019-45-6

Basic information

• Product Name: (4-AMINO-3-FLUORO-PHENYL)-METHANOL
• Synonyms: 4-AMINO-3-FLUOROBENZYL ALCOHOL;(4-AMINO-3-FLUORO-PHENYL)-METHANOL;2-Fluoro-4-(hydroxymethyl)aniline, (4-Amino-3-fluorophenyl)methanol
• CAS NO: 146019-45-6
• Molecular Formula: C₇H₈FNO
• Molecular Weight: 141.14
• Product Categories: pharmacetical
• Mol File: 146019-45-6.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: (4-AMINO-3-FLUORO-PHENYL)-METHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: (4-AMINO-3-FLUORO-PHENYL)-METHANOL(146019-45-6)
• EPA Substance Registry System: (4-AMINO-3-FLUORO-PHENYL)-METHANOL(146019-45-6)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 146019-45-6(Hazardous Substances Data)

Usage

General Description

(4-AMINO-3-FLUORO-PHENYL)-METHANOL is a chemical compound with the molecular formula C7H7FNO. It is a derivative of phenol and contains both an amino group and a fluorine atom. (4-AMINO-3-FLUORO-PHENYL)-METHANOL is used in the synthesis of pharmaceuticals and agrochemicals, and it also has potential applications in materials and organic electronics. It may also be used as a building block in the synthesis of more complex organic molecules. The presence of the fluorine atom in the compound also gives it unique properties and potential in various chemical reactions and processes. Overall, (4-AMINO-3-FLUORO-PHENYL)-METHANOL has diverse and important applications in the field of chemistry and related industries.

Upstream product

• 403-21-4 3-fluoro-4-nitrobenzoic acid 
• 455-87-8 4-amino-3-fluorobenzoic acid 

Relevant articles and documents

Mechanistic Evaluation of Bioorthogonal Decaging with trans-Cyclooctene: The Effect of Fluorine Substituents on Aryl Azide Reactivity and Decaging from the 1,2,3-Triazoline

Bioorthogonal prodrug activation/decaging strategies need to be selective, rapid and release the drug from the masking group upon activation. The rates of the 1,3-dipolar cycloaddition between a trans-cyclooctene (TCO) and a series of fluorine-substituted

HUMAN PLASMA KALLIKREIN INHIBITORS

Disclosed are compounds of formula (I), as described herein, and pharmaceutically acceptable salts thereof. The compounds are inhibitors of plasma kallikrein. Also provided are pharmaceutical compositions comprising at least one compound of the invention, and methods involving use of the compounds and compositions of the invention in the treatment and prevention of diseases and conditions characterized by unwanted plasma kallikrein activity.