1460285-33-9Relevant academic research and scientific papers
Functionalized N-containing heterocyclic scaffolds derived from N-substituted pyrroles via inter- and intramolecular annulations
Shao, Nana,Li, Jinbiao,Zhu, Huajian,Zhang, Shuaizhong,Zou, Hongbin
, p. 6088 - 6094 (2018)
Two series of N-containing heterocycles were synthesized by one-step intramolecular or intermolecular annulations of N-substituted pyrrole-2-carbaldehydes and pyrrole-2-carbonitriles. These facile and atom-economic synthetic routes involved the inherent three potential electrophilic and nucleophilic reactive sites of the synthons and the reaction solvent plays a crucial role leading to these different types of products. Additionally, plausible mechanisms are proposed.
BICYCLIC PYRAZINONE DERIVATIVES
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Page/Page column 60, (2013/10/21)
Compounds of the formula (I) in which R1, X and Y have the meanings indicated in Claim 1, are inhibitors of Tankyrase, and can be employed, inter alia, for the treatment of diseases such as cancer, cardiovascular diseases, central nervous syste
