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(S)-2-(4-methylphenyl)-butane, also known as (S)-2-(p-tolyl)butane, is a chiral organic compound with the molecular formula C??H??. It features a butane chain with a 4-methylphenyl group attached to the second carbon atom. The compound exhibits stereochemistry due to the presence of a chiral center at the second carbon, with the (S)-configuration indicating that the substituent with the higher priority (4-methylphenyl) is on the left side when looking at the molecule along the bond connecting the chiral center to the first carbon. (S)-2-(4-methylphenyl)-butane is of interest in organic chemistry and may have potential applications in the synthesis of pharmaceuticals and other specialty chemicals.

1461-12-7

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1461-12-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1461-12-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,4,6 and 1 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1461-12:
(6*1)+(5*4)+(4*6)+(3*1)+(2*1)+(1*2)=57
57 % 10 = 7
So 1461-12-7 is a valid CAS Registry Number.

1461-12-7Upstream product

1461-12-7Downstream Products

1461-12-7Relevant academic research and scientific papers

Asymmetric hydrogenation of α-ethylstyrenes catalyzed by chiral ruthenium complexes

Forman,Ohkuma,Hems,Noyori

, p. 9471 - 9475 (2000)

A combined system of RuCl2[(R,R)-Me-DuPhos](dmf)(n) and t-C4H9OK catalyzes the asymmetric hydrogenation of α-ethylstyrene derivatives. The reaction proceeds with a substrate to catalyst molar ratio of up to 2600 in 2-propanol at 8 atm and room temperature to give the chiral saturated products in 81-89% ee. (C) 2000 Elsevier Science Ltd.

Diphenylamine-amine-oxazoline ligand, synthesis method as well as metal complex and application thereof

-

Paragraph 0105; 0106; 0108; 0109; 0110; 0111; 0112; 0113, (2019/04/17)

The invention provides a diphenylamine-amine-oxazoline ligand which is a compound of formula (1) or an antipode or racemate of the compound of formula (1), wherein R1 and R2 are respectively and separately one of C1 to C10 hydrocarbon group, benzyl group, phenyl group or substituted phenyl group and heteroaryl group; and R3 is H or methyl. The invention also discloses a synthesis method as well asa metal complex and application thereof, which aims at providing a catalyst capable of realizing high synthesis yield by virtue of a simple synthesis route, and ensuring that the catalyst has very high catalytic activity in asymmetric hydrogenation and hydrogen transfer reactions of olefins and ketones.

Propylene carbonate as a solvent for asymmetric hydrogenations

Bayardon, Jerome,Holz, Jens,Schaeffner, Benjamin,Andrushko, Vasyl,Verevkin, Sergej,Preetz, Angelika,Boerner, Armin

, p. 5971 - 5974 (2008/09/17)

(Figure Presented) A penny saved is a penny earned: The use of propylene carbonate as the solvent in iridium-catalyzed hydrogenations of non-functionalized olefins allows efficient catalyst recycling through the formation of two-phase mixtures with nonpolar solvents such as n-hexane. In the picture, the hydrogenated tetrahydronaphthalene derivative is extracted into the hydrocarbon phase.

Iridium-catalyzed enantioselective hydrogenation of terminal alkenes

McIntyre, Steven,Hoermann, Esther,Menges, Frederik,Smidt, Sebastian P.,Pfaltz, Andreas

, p. 282 - 288 (2007/10/03)

Iridium complexes derived from chiral P,N ligands are efficient catalysts for the enantioselective hydrogenation of 2-aryl-substituted terminal alkenes. Using 0.1-1 mol % of catalyst at room temperature and ambient hydrogen pressure, high enantioselectivi

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