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2-Azabicyclo[2.2.2]octane-3-carboxylic acid, also known as (R)-(9CI), is a chemical compound with a bicyclic structure that includes a nitrogen atom. It is a carboxylic acid and is utilized in the development of pharmaceuticals, particularly as a building block for the synthesis of various drugs. The (R)-(9CI) designation denotes the stereochemistry of the compound, which is crucial for its specific applications and interactions.

146144-65-2

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146144-65-2 Usage

Uses

Used in Pharmaceutical Industry:
2-Azabicyclo[2.2.2]octane-3-carboxylic acid, (R)-(9CI), is used as a key intermediate in the synthesis of pharmaceutical compounds. Its unique bicyclic structure and carboxylic acid functionality make it a valuable building block for creating a variety of drugs with different therapeutic properties.
Used in Organic Synthesis:
In the field of organic synthesis, 2-Azabicyclo[2.2.2]octane-3-carboxylic acid, (R)-(9CI), serves as an important intermediate. Its specific stereochemistry and functional groups allow for the development of complex organic molecules with potential applications in various industries, including pharmaceuticals, agrochemicals, and materials science.
Used in Chiral Compounds Production:
The (R)-(9CI) designation highlights the importance of stereochemistry in the compound's properties and applications. 2-Azabicyclo[2.2.2]octane-3-carboxylic acid, (R)-(9CI), is used in the production of chiral compounds, which are essential in various chemical and pharmaceutical processes. The specific arrangement of atoms around the chiral center ensures that the resulting compounds have the desired stereochemistry for their intended applications.

Check Digit Verification of cas no

The CAS Registry Mumber 146144-65-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,6,1,4 and 4 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 146144-65:
(8*1)+(7*4)+(6*6)+(5*1)+(4*4)+(3*4)+(2*6)+(1*5)=122
122 % 10 = 2
So 146144-65-2 is a valid CAS Registry Number.

146144-65-2Downstream Products

146144-65-2Relevant academic research and scientific papers

Synthesis and Conformational Studies of Zabicipril (S9650-3), a Potent Inhibitor of Angiotensin Converting Enzyme

Vincent, Michel,Pascard, Claudine,Cesario, Michele,Remond, Georges,Bouchet, Jean-Paul,et al.

, p. 7369 - 7372 (2007/10/02)

The synthesis of the title compound 8c is described.This inhibitor of Angiotensin Converting Enzyme (ACE) contains aza-2 bicyclooctane-carboxylic acid, a bulky cyclic amino acid replacing the proline moiety present in most ACE inhibitors described

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