1461634-28-5

Basic information

• Product Name: (2,2-difluorocyclopropyl)(4-nitrophenyl)methanone
• Synonyms: (2,2-difluorocyclopropyl)(4-nitrophenyl)methanone
• CAS NO: 1461634-28-5
• Molecular Weight: 227.167
• Mol File: 1461634-28-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2,2-difluorocyclopropyl)(4-nitrophenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (2,2-difluorocyclopropyl)(4-nitrophenyl)methanone(1461634-28-5)
• EPA Substance Registry System: (2,2-difluorocyclopropyl)(4-nitrophenyl)methanone(1461634-28-5)

Safety Data

• Hazardous Substances Data: 1461634-28-5(Hazardous Substances Data)

Upstream product

• 100-19-6 (4-nitrophenyl)ethanone 
• 22731-72-2 1-(4-nitrophenyl)prop-2-en-1-one 
• 120801-75-4 trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate 

Downstream Products

• 1461634-39-8 (5-fluoro-2-methyl-1H-pyrrol-3-yl)(4-nitrophenyl)methanone 
• 1529771-20-7 4,4,4-trifluoro-1-(4-nitrophenyl)butan-1-one 
• 1529771-26-3 4-chloro-4,4-difluoro-1-(4-nitrophenyl)butan-1-one 
• 1529771-36-5 4-bromo-4,4-difluoro-1-(4-nitrophenyl)butan-1-one 

Relevant articles and documents

Boron-trihalide-promoted regioselective ring-opening reactions of gem-difluorocyclopropyl ketones

Boron trihalide-promoted ring-opening reactions of gem-difluorocyclopropyl ketones to give the corresponding β-trifluoromethyl ketones and β-halodifluoromethyl ketones were described. It was found that boron trihalides act as both Lewis acids and nucleophiles and the proximal bond prefers to cleave in this transformation.