14618-90-7Relevant academic research and scientific papers
Oxidative rearrangement of 2-alkoxy-3,4-dihydro-2H-pyrans: stereocontrolled synthesis of 4,5-cis-disubstituted tetrahydrofuranones including whisky and cognac lactones and crobarbatic acid
Armstrong, Alan,Ashraff, Cassim,Chung, Hunsuk,Murtagh, Lorraine
experimental part, p. 4490 - 4504 (2009/10/09)
Oxidation of 2-alkoxy-3,4-dihydro-2H-pyrans 3 with dimethyldioxirane or MTO/urea-H2O2 followed by Jones oxidation leads to rearrangement and stereocontrolled formation of 4,5-cis-disubstituted tetrahydrofuranones. The method is applied to the synthesis of the whisky lactone 9, cognac lactone 10 and crobarbatic acid 17.
Platinum-catalyzed addition of dimethylsilylene to β-methyl α-β-unsaturated ketones: γ-silylation forming 1-Oxa-2-silacyclohex-5-enes
Okamoto, Kazuhiro,Hayashi, Tamio
, p. 5067 - 5069 (2008/03/27)
The reaction of β-methyl α,β-unsaturated ketones with pentamethyldisilane in the presence of a platinum catalyst brought about silylation on the β-methyl group giving high yields of oxasilacyclohexenes.
