146196-91-0

Basic information

• Product Name: Flavanone-d5
• Synonyms: Flavanone-d5;2,3-Dihydro-2-(phenyl-d5)-
• CAS NO: 146196-91-0
• Molecular Formula: C₁₅H₁₂O₂
• Molecular Weight: 229
• Product Categories: Aromatics;Heterocycles;Impurities;Intermediates & Fine Chemicals;Isotope Labelled Compounds;Pharmaceuticals;Aromatics, Heterocycles, Impurities, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 146196-91-0.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: Refrigerator, under inert atmosphere
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• CAS DataBase Reference: Flavanone-d5(CAS DataBase Reference)
• NIST Chemistry Reference: Flavanone-d5(146196-91-0)
• EPA Substance Registry System: Flavanone-d5(146196-91-0)

Safety Data

• Hazardous Substances Data: 146196-91-0(Hazardous Substances Data)

Usage

Uses

Labelled Propafenone (P757500) impurity.

Upstream product

• 1312417-21-2 C₁₅H₇⁽²⁾H₅O₃ 
• 98-88-4 benzoyl chloride 

Relevant articles and documents

An efficient one-pot synthesis of flavones

Flavones were prepared using a one-pot procedure starting from the corresponding 2′-hydroxyacetophenones. The latter were treated with 3 equiv of aroyl chloride in wet K2CO3/acetone (1% w/w water) to afford a good yield of flavone and a smaller amount of 3-aroylflavone. Evidence was obtained that the reaction proceeds via a triketone intermediate. When the reactants were heated in 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) and pyridine, the 3-aroylflavone was obtained exclusively. Use of a stoichiometric amount of aroyl chloride afforded only the corresponding flavone.