146196-93-2

Basic information

• Product Name: (2E)-1-(2-Hydroxyphenyl)-3-(phenyl-d5)-2-propen-1-one
• Synonyms: (2E)-1-(2-Hydroxyphenyl)-3-(phenyl-d5)-2-propen-1-one;(E)-2'-Hydroxy-chalcone-d5;(E)-o-Hydroxyphenyl Styryl Ketone-d5;NSC 170284-d5;trans-2'-Hydroxychalcone-d5
• CAS NO: 146196-93-2
• Molecular Formula: C₁₅H₁₂O₂
• Molecular Weight: 224.25458
• Product Categories: Aromatics;Intermediates & Fine Chemicals;Isotope Labelled Compounds;Pharmaceuticals;Aromatics, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 146196-93-2.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (2E)-1-(2-Hydroxyphenyl)-3-(phenyl-d5)-2-propen-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (2E)-1-(2-Hydroxyphenyl)-3-(phenyl-d5)-2-propen-1-one(146196-93-2)
• EPA Substance Registry System: (2E)-1-(2-Hydroxyphenyl)-3-(phenyl-d5)-2-propen-1-one(146196-93-2)

Safety Data

• Hazardous Substances Data: 146196-93-2(Hazardous Substances Data)

Usage

Uses

A labelled synthetic chalcone with antibacterial and potential antitumoral activity.

Upstream product

• 14132-51-5 2,3,4,5,6-pentadeuteriobenzaldehyde 
• 118-93-4 o-hydroxyacetophenone 

Relevant articles and documents

Studies on the metabolism of propafenone. 1st comm.: Synthesis and chromatographic/mass spectrometric properties of the labelled compound and of the reference substances

The synthesis of 14C-propafenone and 2H-propafenone (propafenone: 2-(2'-hydroxy-3'-propylamino-propoxy)-ω-phenyl-propiophenone hydrochloride) and some reference compounds is described. The thin-layer chromatographic, high-performance liquid and gas chromatographic properties of the substances are described. Propafenone and the reference substances were studied by mass spectrometry and compared with each other, with respect to structural elucidation of the metabolites. The chromatographic and mass spectrometric data (key ions) enables the metabolites of propafenone to be identified in biological material.