146203-19-2Relevant academic research and scientific papers
Nucleosides. 5. Synthesis of Guanine and Formycin B Derivatives as Potential Inhibitors of Purine Nucleoside Phosphorylase
Chern, Ji-Wang,Lee, Horng-Yuh,Chen, Chien-Shu,Shewach, Donna S.,Daddona, Peter E.,Townsend, Leroy B.
, p. 1024 - 1031 (2007/10/02)
In an effort to develop potent human purine nucleoside phosphorylase (PNP) inhibitors as immunosuppressive and chemotherapeutic agents, several 8-aminoguanine derivatives were synthesized and evaluated as potential PNP inhibitors.These studies were design
