146205-02-9Relevant articles and documents
Guaianolide sesquiterpene lactones, a source to discover agents that selectively inhibit acute myelogenous leukemia stem and progenitor cells
Zhang, Quan,Lu, Yaxin,Ding, Yahui,Zhai, Jiadai,Ji, Qing,Ma, Weiwei,Yang, Ming,Fan, Hongxia,Long, Jing,Tong, Zhongsheng,Shi, Yehui,Jia, Yongsheng,Han, Bin,Zhang, Wenpeng,Qiu, Chuanjiang,Ma, Xiaoyan,Li, Qiuying,Shi, Qianqian,Zhang, Haoliang,Li, Dongmei,Zhang, Jing,Lin, Jianping,Li, Lu-Yuan,Gao, Yingdai,Chen, Yue
, p. 8757 - 8769 (2013/01/15)
Small molecules that can selectively target cancer stem cells (CSCs) remain rare currently and exhibit no common structural features. Here we report a series of guaianolide sesquiterpene lactones (GSLs) and their derivatives that can selectively eradicate