146205-64-3

Upstream product

• 186581-53-3 diazomethane 
• 33878-99-8 (S)-8a-methyl-3,4,8,8a-tetrahydro-2H,7H-naphthalene-1,6-dione 
• 146205-63-2 (1S,8aS)-1-(tert-Butyl-dimethyl-silanyloxy)-7-hydroxy-8a-methyl-6-oxo-1,2,3,4,6,7,8,8a-octahydro-naphthalene-1-carbonitrile 
• 146205-77-8 Acetic acid (8S,8aS)-8-(tert-butyl-dimethyl-silanyloxy)-8-cyano-8a-methyl-3-oxo-1,2,3,5,6,7,8,8a-octahydro-naphthalen-2-yl ester 
• 145632-33-3 (S)-7a′-methyl-2′,3′,7′,7a′-tetrahydrospiro[[1,3]dithiolane-2,5′-inden]-1′(6′H)-one 
• 146205-62-1 (1S,8aS)-1,2,3,4,8,8a-hexahydro-1-<oxy>-8a-methyl-6(7H)-oxonaphthalene-1-carbonitrile 
• 145632-91-3 (4'aS,5'S)-4',4'a,5',6',7',8'-hexahydro-5'-<oxy>-4a'-methylspiro<1,3-dithiolane-2,2'(3'H)-naphthalene>-5'-carbonitrile 

Relevant academic research and scientific papers

An enantioselective approach to ring A of taxol using the Wieland-Miescher ketone

The selective protection of the S-(+)-enantiomer of the Wieland Miescher ketone (2) as the tert-butyldimethylsilyl-protected cyanohydrin 7 and the oxidative cleavage of an α-ketol 8 that was derived from 7 provided a model 10 for the A ring of the taxol (