14621-02-4

Basic information

• Product Name: 4-Pyridinecarboxamide, N-(4-methoxyphenyl)-
• Synonyms: 4-Pyridinecarboxamide, N-(4-methoxyphenyl)-;Isonicotin-4-methoxyanilid;Isonicotinsaeure-p-anisidid;Isonicotinsaeure-4-methoxyanilid;isonicotinic acid p-anisidide
• CAS NO: 14621-02-4
• Molecular Formula: C13H12N2O2
• Molecular Weight: 228.25
• Mol File: 14621-02-4.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 4-Pyridinecarboxamide, N-(4-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Pyridinecarboxamide, N-(4-methoxyphenyl)-(14621-02-4)
• EPA Substance Registry System: 4-Pyridinecarboxamide, N-(4-methoxyphenyl)-(14621-02-4)

Safety Data

• Hazardous Substances Data: 14621-02-4(Hazardous Substances Data)

Upstream product

• 55-22-1 pyridine-4-carboxylic acid 
• 104-94-9 4-methoxy-aniline 
• 1120-87-2 4-bromopyridin 
• 13939-06-5 molybdenum hexacarbonyl 
• 29684-56-8 Burgess Reagent 
• 94-53-1 Piperonylic acid 
• 14254-57-0 4-(chlorocarbonyl)pyridine 

Downstream Products

• 183436-47-7 3-Hydroxy-2-(4-methoxy-phenyl)-2,3-dihydro-pyrrolo[3,4-c]pyridin-1-one 
• 1389293-15-5 C₂₀H₂₀N₂O₄ 
• 1329663-55-9 C₄₁H₃₀N₂O₂ 
• 1329663-57-1 C₄₀H₂₇ClN₂O 
• 27060-33-9 thioisonicotinic acid p-anisidide 
• 898564-62-0 4-[1-(4-methoxy-phenyl)-1H-imidazol-2-yl]-pyridine 

Relevant articles and documents

Aminocarbonylation of N -Containing Heterocycles with Aromatic Amines Using Mo(CO) 6

We describe herein the palladium-catalyzed aminocarbonylation of nitrogen-containing heterocycles with aniline derivatives using molybdenum hexacarbonyl as a CO solid source, expanding the scope of the limited examples. This method is compatible with a variety of substitutions on the aniline moiety. The simple reaction conditions include easily available Pd(dppf)Cl 2 catalyst, DBU as base in DMF at 120 °C for 3 hours in sealed tube thereby leading to the isolation of 21 compounds with yields ranging from 18 to 82%. We also show that double aminocarbonylation reactions are possible in satisfactory yields regarding both coupling partners.

BICYCLIC HETEROARYL COMPOUNDS AS PDE10 INHIBITORS

The invention pertains to bicyclic heteroaryl compounds that serve as effective phosphodiesterase (PDE) inhibitors The invention also relates to compounds which are selective inhibitors of PDE-10. The invention further relates to intermediates for prepara

Activation of carboxylic acids by Burgess reagent: An efficient route to acyl ureas and amides

Carboxylic acids upon treatment with Burgess reagent are converted to novel mixed sulfocarboxy anhydrides. Subsequent treatment of such mixed anhydrides with amines at elevated temperatures yields acyl ureas and amides. The ratio of the two products appears to be temperature controlled. The method provides a simple and convenient route to diverse acyl ureas starting from carboxylic acids and amines.