146253-86-3 Usage
Check Digit Verification of cas no
The CAS Registry Mumber 146253-86-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,6,2,5 and 3 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 146253-86:
(8*1)+(7*4)+(6*6)+(5*2)+(4*5)+(3*3)+(2*8)+(1*6)=133
133 % 10 = 3
So 146253-86-3 is a valid CAS Registry Number.
InChI:InChI=1/C25H29ClN2O8S/c1-28(2)18-17-20(31)14-11(9-37-8-4-7-26)10-5-3-6-12(29)13(10)19(30)15(14)22(33)25(17,36)23(34)16(21(18)32)24(27)35/h3,5-6,11,14,17-18,20,29-31,35-36H,4,7-9,27H2,1-2H3/b24-16-/t11-,14+,17+,18-,20-,25-/m0/s1
146253-86-3Relevant articles and documents
Inhibition of the Tetracycline Efflux Antiport Protein by 13-Thio-Substituted 5-Hydroxy-6-deoxytetracyclines
Nelson, Mark L.,Park, Britt H.,Andrews, Janey S.,Georgian, Vlasios A.,Thomas, Richard C.,Levy, Stuart B.
, p. 370 - 377 (2007/10/02)
A series of 13-(alkylthio) and 13-(arylthio) derivatives of 5-hydroxy-6-deoxytetracycline (tetracycline, Tc) were synthesized and compared to the clinically used antibiotics tetracycline, methacycline, and minocycline for their ability to inhibit tetracyc