146257-03-6

Basic information

• Product Name: 1-BOC-3-METHOXYPYRROLIDINE
• Synonyms: 1-BOC-3-METHOXYPYRROLIDINE
• CAS NO: 146257-03-6
• Molecular Formula: C10H19NO3
• Molecular Weight: 201.26276
• Product Categories: pharmacetical
• Mol File: 146257-03-6.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 253.9±33.0 °C(Predicted)
• Appearance: /
• Density: 1.04±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: -2.57±0.40(Predicted)
• CAS DataBase Reference: 1-BOC-3-METHOXYPYRROLIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BOC-3-METHOXYPYRROLIDINE(146257-03-6)
• EPA Substance Registry System: 1-BOC-3-METHOXYPYRROLIDINE(146257-03-6)

Safety Data

• Hazardous Substances Data: 146257-03-6(Hazardous Substances Data)

Usage

General Description

1-BOC-3-METHOXYPYRROLIDINE is a chemical compound used in organic synthesis and pharmaceutical research. It is a derivative of pyrrolidine, a five-membered nitrogen-containing heterocycle. The "1-BOC" in its name refers to the tert-butoxycarbonyl (BOC) protecting group, which is often used in organic chemistry to temporarily shield reactive functional groups from unwanted reactions. The "3-METHOXY" portion designates the presence of a methoxy (OCH3) group attached to the third carbon atom of the pyrrolidine ring. 1-BOC-3-METHOXYPYRROLIDINE is commonly used as a building block in the synthesis of various pharmaceuticals and other biologically active molecules due to its versatility and reactivity. Its unique structural features and functional groups make it a valuable intermediate in the production of diverse chemical compounds with potential therapeutic uses.

Upstream product

• 103057-44-9 N-(tert-butoxycarbonyl)-3-hydroxypyrrolidine 
• 124-63-0 methanesulfonyl chloride 
• 74-88-4 methyl iodide 

Downstream Products

• 1201657-89-7 tert-butyl 3-(4-bromo-1H-pyrazol-1-yl) pyrrolidine-1-carboxylate 
• 136725-50-3 (+/-)-3-methoxypyrrolidine hydrochloride 
• 62848-20-8 3-methoxy-pyrrolidine 

Relevant articles and documents

From a novel HTS hit to potent, selective, and orally bioavailable KDM5 inhibitors

A high-throughput screening (HTS) of the Genentech/Roche library identified a novel, uncharged scaffold as a KDM5A inhibitor. Lacking insight into the binding mode, initial attempts to improve inhibitor potency failed to improve potency, and synthesis of

NEW BRADYKININ B1 ANTAGONISTS

The invention relates to compounds of formula (I) where in R1, R1a, R1b, R2, R3 and X, X1, X2, X3 have the meaning as cited in the description and the claims. Said compounds are useful as Bradykinin B1 antagonists. The invention also relates to pharmaceutical compositions, the preparation of such compounds as well as the production and use as medicament.

1 H-INDAZOLES, BENZOTHIAZOLES, 1,2-BENZOISOXAZOLES, 1,2-BENZOISOTHIAZOLES, AND CHROMONES AND PREPARATION AND USES THEREOF

The present invention relates generally to the field of ligands for nicotinic acetylcholine receptors (nAChR), activation of nAChRs, and the treatment of -disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain. Further, this invention relates to novel compounds (indazoles and benzothiazoles), which act as ligands for the α7 nAChR subtype, methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.