146273-84-9

Basic information

• Product Name: 7-Hydroxy-8,9-dimethoxy-5-phenyl-4,5-dihydro-3H-benzo[b]oxepin-2-one
• CAS NO: 146273-84-9
• Molecular Weight: 314.338
• Mol File: 146273-84-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 7-Hydroxy-8,9-dimethoxy-5-phenyl-4,5-dihydro-3H-benzo[b]oxepin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 7-Hydroxy-8,9-dimethoxy-5-phenyl-4,5-dihydro-3H-benzo[b]oxepin-2-one(146273-84-9)
• EPA Substance Registry System: 7-Hydroxy-8,9-dimethoxy-5-phenyl-4,5-dihydro-3H-benzo[b]oxepin-2-one(146273-84-9)

Safety Data

• Hazardous Substances Data: 146273-84-9(Hazardous Substances Data)

Upstream product

• 1008-76-0 4,5-dihydro-5-phenyl-2(3H)-furanone 
• 52643-52-4 2,3-dimethoxybenzene-1,4-diol 

Relevant articles and documents

Preparation and pharmacological evaluation of 4-(1,4-benzoquinon-2-yl)-4-phenylbutanamides as potential cerebral protective agents

A new series of 4-(1,4-benzoquinon-2-yl)-4-phenylbutanamides (2) were synthesized for evaluation of their pharmacological activities. All these compounds synthesized showed significant antilipidperoxidation (ALP) activities with brain homogenate in rats and some of them possessed a protective effect against hypobaric hypoxia in mice. Especially, a thiomorpholine derivative (21, SUN-4757) showed a wide efficacy spectrum to a variety of experimental screening assays designed for cerebral protective agents, and it had a high LD50 value.