146301-47-5Relevant academic research and scientific papers
A Desulfonylative Approach in Oxidative Gold Catalysis: Regiospecific Access to Donor-Substituted Acyl Gold Carbenes
Chen, Hongyi,Zhang, Liming
, p. 11775 - 11779 (2015)
Donor-substituted acyl gold carbenes are challenging to access selectively by gold-promoted intermolecular oxidation of internal alkynes as the opposite regioisomers frequently predominate. By using alkynyl sulfones or sulfonates as substrates, the oxidative gold catalysis in the presence of substituted pyridine N-oxides offers regiospecific access to acyl/aryl, acyl/alkenyl, and acyl/alkoxy gold carbenes by in situ expulsion of sulfur dioxide. The intermediacies of these reactive species are established by their reactivities, including undergoing further oxidation by the same oxidant, cyclopropanation of styrenes, engaging in a [3+2] cycloaddition with α-methylstyrene, and conversion into dienones. Accept it: A desulfonylative approach was developed to regiospecifically access these underexplored acyl gold carbenes from either alkynyl aryl/alkenyl sulfones or alkynyl sulfonate substrates. The reactivities of these donor- and acceptor-substituted carbenes are examined.
Preparation of N,N-disubstituted (1-alkyne)- and (E)-(1-alkene)-sulfinamides and their conversion into the corresponding sulfinates or sulfonamides
Baudin, Jean-Bernard,Julia, Sylvestre A.,Wang, Yuan
, p. 952 - 962 (2007/10/02)
Treatment of (1-piperidine)- or (4-morpholine)-sulfinyl chloride with unsaturated lithio, bromomagnesio or diisobutylalumino derivatives afforded the title sulfinamides 3 and 5.The 1-alkynesulfinamides 3 were smoothly reduced with lithium aluminium hydrid
