146307-07-5

Upstream product

• 146307-06-4 4-(5-chloro-2-oxo-1,2-dihydropyrimidin-1-ylmethoxymethyl)benzoic acid 
• 88045-96-9 4-(5-chloro-2-oxo-1,2-dihydropyrimidin-1-ylmethoxymethyl)benzoic acid methyl ester 

Downstream Products

• 146307-10-0 2-<4-(5-chloro-2-oxo-1,2-dihydropyrimidin-1-ylmethoxymethyl)benzamido>succinic acid dibenzyl ester 
• 146307-09-7 2-<4-(5-chloro-2-oxo-1,2-dihydropyrimidin-1-ylmethoxymethyl)benzamido>succinic acid dimethyl ester 
• 146307-12-2 2-<4-(5-chloro-2-oxo-1,2-dihydropyrimidin-1-ylmethoxymethyl)benzamido>pentanedioic acid dibenzyl ester 
• 146307-11-1 2-<4-(5-chloro-2-oxo-1,2-dihydropyrimidin-1-ylmethoxymethyl)benzamido>-3-phenylpropionic acid benzyl ester 
• 146307-08-6 2-<4-(5-chloro-2-oxo-1,2-dihydropyrimidin-1-ylmethoxymethyl)benzamido>-3-phenylpropionic acid methyl ester 

Relevant academic research and scientific papers

Synthesis of pyrimidine derivatives of amino acids using pig liver esterase and pancreas lipase.

The parent methyl ester of the N-1 substituted 5-chloropyrimidinone is hydrolysed by pig liver esterase to the corresponding carboxylic acid. The acid chloride was made with PCl5 in toluene, and coupling with benzyl and methyl esters of selected L-amino a