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Neurotrophin-4, HUMAN, also known as NT-4, is a protein that functions as a growth factor in the nervous system. It is a vital component of the neurotrophin family, which includes nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF). NT-4 is instrumental in the development, maintenance, and survival of neurons, as well as in the promotion of their differentiation. It also supports the growth and maintenance of neuronal connections, playing a significant role in synaptic plasticity, which is crucial for learning and memory processes. Research indicates that NT-4 has the potential to facilitate neuronal regeneration and repair in various neurodegenerative conditions and injuries to the nervous system.

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  • 146318-03-8 Structure
  • Basic information

    1. Product Name: NEUROTROPHIN-4, HUMAN
    2. Synonyms: HUMAN NEUROTROPHIC 4/5;HUMAN NEUROTROPHIC 5;HUMAN NEUROTROPHIC FACTOR-4;HUMAN NEUROTROPHIN 4;HUMAN NT-4;HUMAN NT-4/NT-5;HUMAN NT-5;RECOMBINANT HUMAN NT-4
    3. CAS NO:146318-03-8
    4. Molecular Formula: C15H24N5O16P3
    5. Molecular Weight: 623.296243
    6. EINECS: N/A
    7. Product Categories: monoclonal antibody
    8. Mol File: 146318-03-8.mol
    9. Article Data: 0
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /lyophilized powder
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: −20°C
    8. Solubility: N/A
    9. CAS DataBase Reference: NEUROTROPHIN-4, HUMAN(CAS DataBase Reference)
    10. NIST Chemistry Reference: NEUROTROPHIN-4, HUMAN(146318-03-8)
    11. EPA Substance Registry System: NEUROTROPHIN-4, HUMAN(146318-03-8)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany: 3
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 146318-03-8(Hazardous Substances Data)

146318-03-8 Usage

Uses

Used in Pharmaceutical Industry:
Neurotrophin-4, HUMAN is used as a therapeutic agent for promoting neuronal survival and differentiation. It is particularly beneficial in the treatment of neurodegenerative diseases and injuries to the nervous system, where it can stimulate neuronal regeneration and repair.
Used in Research Applications:
Neurotrophin-4, HUMAN is used as a research tool for studying the development and function of the nervous system. It aids in understanding the mechanisms of synaptic plasticity and the role of neurotrophic factors in learning and memory processes.
Used in Drug Development:
Neurotrophin-4, HUMAN is utilized in the development of drugs targeting neurodegenerative diseases. Its potential to promote neuronal regeneration and repair makes it a promising candidate for the creation of novel therapeutics aimed at treating conditions such as Alzheimer's disease, Parkinson's disease, and spinal cord injuries.

Check Digit Verification of cas no

The CAS Registry Mumber 146318-03-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,6,3,1 and 8 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 146318-03:
(8*1)+(7*4)+(6*6)+(5*3)+(4*1)+(3*8)+(2*0)+(1*3)=118
118 % 10 = 8
So 146318-03-8 is a valid CAS Registry Number.

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