14633-89-7

Upstream product

• 119-61-9 benzophenone 
• 59983-62-9 Li{(CH₂)(CH₂)P(C₆H₅)2} 
• 530-48-3 1,1-Diphenylethylene 
• 4559-70-0 Diphenylphosphine oxide 
• 108-86-1 bromobenzene 

Downstream Products

• 78375-70-9 1,1-diphenyl-2-diphenylphosphinylethene oxide 
• 117924-19-3 [2-(Diphenyl-phosphinoyl)-1,1-diphenyl-ethoxy]-trimethyl-silane 

Relevant academic research and scientific papers

Electrochemical Oxidative Phosphorylation of Aldehyde Hydrazones

The electrochemical phosphorylation of aldehyde hydrazones has been developed under exogenous oxidant-free conditions. The strategy provides expedient access to highly functionalized α-iminophosphine oxides with ample scope and broad functional group tole

A phosphoryl radical-initiated Atherton-Todd-type reaction under open air

A phosphoryl radical-initiated Atherton-Todd-type reaction using air as the radical initiator and CHCl3 as the halogenating reagent for the phosphorylation of alcohols, phenols, and amines has been developed. This novel transformation provides a highly efficient route to important phosphinates, phosphinic amides, and phosphoramidates in up to 99% yield with a broad substrate scope under very mild conditions (48 examples).

Phosphinoyl radical-initiated vicinal hydroxy-phosphorylation of alkenes

A protocol of Mn(OAc)3–mediated α,β-hydroxy-phosphorylation of alkenes with phosphorus-centered radicals generated from diphenylphosphine oxide is described. A combination of steric and electronic factors played an important role in this reacti

Copper-catalyzed direct hydroxyphosphorylation of electron-deficient alkenes with H-phosphine oxides and dioxygen

A copper-catalyzed direct hydroxyphosphorylation of electron-deficient alkenes with H-phosphine oxides and dioxygen is reported. The present reaction, proceeds under mild reaction conditions with good functional group tolerance, affording the facile and efficient synthesis of various β-hydroxyphosphine oxides in a scaled-up manner with moderate to good yields.

Dioxygen-induced oxidative activation of a P-H bond: Radical oxyphosphorylation of alkenes and alkynes toward β-oxy phosphonates

The dioxygen-induced radical oxyphosphorylation of alkenes and alkynes is presented, wherein a P-H bond was activated by molecular oxygen. Various β-oxy phosphonates could be facilely synthesized without the assistance of any transition metals or extra or

Solvent-controlled direct radical oxyphosphorylation of styrenes mediated by Manganese(III)

Direct radical oxyphosphorylation of styrenes with diarylphosphine oxides and dialkyl phosphites mediated by Mn(OAc)3 is described. The solvent played a key role in this selective difunctionalization reaction.

Catalyst-free direct difunctionalization of alkenes with H-phosphine oxides and dioxygen: A facile and green approach to β-hydroxyphosphine oxides

A simple and catalyst-free method has been developed for the construction of β-hydroxyphosphine oxides through direct difunctionalization of alkenes with H-phosphine oxides and dioxygen under mild conditions. Preliminary mechanistic studies indicated that the hydroxyl oxygen atom of β-hydroxyphosphine oxide originated from the dioxygen and the present reaction might involve a radical process.

Direct radical acetoxyphosphorylation of styrenes mediated by manganese(III)

Direct radical acetoxyphosphorylation of styrenes mediated by Mn(OAc)3 with diphenylphosphine oxide and dialkyl phosphites was described, and a new type of difunctionalization of alkenes was achieved.

Reactivity of phosphonium diylids with aldehydes and ketones

Non-stabilized and semi-stabilized phosphonium diylids of the type (C6H5)2P(CHR)(CHLiR) (5) show a greater nucleophilic reactivity toward carbonyl compounds than the corresponding monoylids (C6H5)2P(CHR)(CH2R) (8).Thus diylid 5a reacts readily at room temperature with sterically hindered ketones such as fenchone or di-t-butylketone.However, the residual negative charge in the intermediate adduct 13 slows the decomposition to Wittig products and is probably responsible for the observed changes (generally enhancement) in the E-selectivity in the case of non-stabilized as well as semi-stabilized ylids.