14633-90-0

Upstream product

• 119-61-9 benzophenone 
• 1486-28-8 diphenyl(methyl)phosphine 
• 74-88-4 methyl iodide 
• 59983-62-9 Li{(CH₂)(CH₂)P(C₆H₅)2} 

Relevant academic research and scientific papers

Reactivity of phosphonium diylids with aldehydes and ketones

Non-stabilized and semi-stabilized phosphonium diylids of the type (C6H5)2P(CHR)(CHLiR) (5) show a greater nucleophilic reactivity toward carbonyl compounds than the corresponding monoylids (C6H5)2P(CHR)(CH2R) (8).Thus diylid 5a reacts readily at room temperature with sterically hindered ketones such as fenchone or di-t-butylketone.However, the residual negative charge in the intermediate adduct 13 slows the decomposition to Wittig products and is probably responsible for the observed changes (generally enhancement) in the E-selectivity in the case of non-stabilized as well as semi-stabilized ylids.