146344-96-9

Basic information

• Product Name: (Z)-7-[(1S,2S,3R,4S,5R)-3-Benzenesulfonylamino-5-(tert-butyl-diphenyl-silanyloxy)-bicyclo[2.2.1]hept-2-yl]-hept-5-enoic acid methyl ester
• CAS NO: 146344-96-9
• Molecular Weight: 645.935
• Mol File: 146344-96-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (Z)-7-[(1S,2S,3R,4S,5R)-3-Benzenesulfonylamino-5-(tert-butyl-diphenyl-silanyloxy)-bicyclo[2.2.1]hept-2-yl]-hept-5-enoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-7-[(1S,2S,3R,4S,5R)-3-Benzenesulfonylamino-5-(tert-butyl-diphenyl-silanyloxy)-bicyclo[2.2.1]hept-2-yl]-hept-5-enoic acid methyl ester(146344-96-9)
• EPA Substance Registry System: (Z)-7-[(1S,2S,3R,4S,5R)-3-Benzenesulfonylamino-5-(tert-butyl-diphenyl-silanyloxy)-bicyclo[2.2.1]hept-2-yl]-hept-5-enoic acid methyl ester(146344-96-9)

Safety Data

• Hazardous Substances Data: 146344-96-9(Hazardous Substances Data)

Upstream product

• 186581-53-3 diazomethane 
• 287395-35-1 (1S,2S,3S,4R)-3-Amino-bicyclo[2.2.1]hept-5-ene-2-carboxylic acid methyl ester 
• 146324-57-4 N-[(1S,2R,3S,4S,6R)-6-(tert-Butyl-diphenyl-silanyloxy)-3-(tetrahydro-pyran-2-yloxymethyl)-bicyclo[2.2.1]hept-2-yl]-benzenesulfonamide 
• 139435-05-5 (1S,2S,3R,4S,5R)-5-tert-butyldiphenylsilyloxy-2-formylmethyl-3-phenylsulfonylaminobicyclo<2.2.1>heptane 
• 139435-01-1 (1S,2S,3R,4S,5R)-5-tert-butyldiphenylsilyloxy-2-hydroxymethyl-3-phenylsulfonylaminobicyclo<2.2.1>heptane 
• 139435-03-3 (1S,2S,3S,4S,5R)-5-tert-butyldiphenylsilyloxy-2-formyl-3-phenylsulfonylaminobicyclo<2.2.1>heptane 
• 146388-63-8 (1S,2S,3S,4S,5R)-5-hydroxy-3-phenylsulfonylamino-(2-tetrahydropyranyloxymethyl)bicyclo<2.2.1>heptane 
• 146388-62-7 (1S,2S,3S,4R)-3-phenylsulfonylamino-(2-tetrahydropyranyloxymethyl)bicyclo<2.2.1>hept-5-ene 
• 139434-98-3 (1S,2S,3S,4R)-2-carbomethoxy-3-phenylsulfonylaminobicyclo<2.2.1>hept-5-ene 
• 139434-97-2 (1S,2S,3S,4R)-3-carbobenzoxyamino-2-carbomethoxybicyclo<2.2.1>hept-5-ene 
• 76197-78-9 (1S,2S,3S,4R)-3-Isocyanato-bicyclo[2.2.1]hept-5-ene-2-carboxylic acid methyl ester 

Downstream Products

• 139435-07-7 (1S,2S,3R,4S,5R)-(5'Z)-7'-(5-hydroxy-3-phenylsulfonylaminobicyclo<2.2.1>hept-2-yl)hept-5'-enoic acid 
• 146324-51-8 (Z)-7-((1S,2S,3R,4S,5R)-3-Benzenesulfonylamino-5-hydroxy-bicyclo[2.2.1]hept-2-yl)-hept-5-enoic acid methyl ester 

Relevant articles and documents

Synthesis of metabolites of S-1452, an orally active thromboxane A2 receptor antagonist

The synthesis of 16 metabolites of S-1452, an orally active thromboxane A2 (TXA2) receptor antagonist, is described. Regioselective hydroxylation at C-5 or C-6 of the bicyclo[2.2.1]heptane skeleton of the optically active intermediat