146405-82-5Relevant academic research and scientific papers
A new stereoselective route to γ-butyrolactones: Asymmetric syntheses of (+)-trans-whisky and (+)-trans-cognac lactones
Miyata,Shinada,Kawakami,Taji,Ninomiya,Naito,Date,Okamura
, p. 2579 - 2581 (2007/10/02)
A new stereoselective route to γ-butyrolactones such as (+)-trans-whisky and (+)-trans-cognac lactones (1a,b) has been developed by a combination of three key reactions: diastereoselective nucleophilic addition of thiophenol, cleavage of chiral N-acylsultam via thioester, and intramolecular displacement of the sulfonium group with carboxylate anion.
