1464150-00-2Relevant academic research and scientific papers
Copper-Catalyzed Diastereoselective Synthesis of Trifluoromethylated Tetrahydrofurans
Wang, Yanan,Jiang, Min,Liu, Jin-Tao
, p. 1322 - 1327 (2016)
The copper-catalyzed intramolecular diastereoselective trifluoromethylcycloetherification of homoallylic alcohols with Togni's reagent as trifluoromethylating reagent was realized under mild conditions. Various trifluoromethylated tetrahydrofurans were synthesized in moderate to good yields. Moreover, a wide range of common functional groups was tolerated.
