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146446-11-9

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146446-11-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 146446-11-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,6,4,4 and 6 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 146446-11:
(8*1)+(7*4)+(6*6)+(5*4)+(4*4)+(3*6)+(2*1)+(1*1)=129
129 % 10 = 9
So 146446-11-9 is a valid CAS Registry Number.

146446-11-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name Gibepyrone F

1.2 Other means of identification

Product number -
Other names 6-Acetyl-3-methyl-pyran-2-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:146446-11-9 SDS

146446-11-9Downstream Products

146446-11-9Relevant articles and documents

Synthetic Studies on Selective, Proapoptotic Isomalabaricane Triterpenoids Aided by Computational Techniques

Boyko, Yaroslav D.,Huck, Christopher J.,Ning, Shang,Shved, Alexander S.,Yang, Cheng,Chu, Tiffany,Tonogai, Emily J.,Hergenrother, Paul J.,Sarlah, David

, p. 2138 - 2155 (2021)

The isomalabaricanes comprise a large family of marine triterpenoids with fascinating structures that have been shown to be selective and potent apoptosis inducers in certain cancer cell lines. In this article, we describe the successful total syntheses of the isomalabaricanes stelletin A, stelletin E, and rhabdastrellic acid A, as well as the development of a general strategy to access other natural products within this unique family. High-throughput experimentation and computational chemistry methods were used in this endeavor. A preliminary structure-activity relationship study of stelletin A revealed the trans-syn-trans core motif of the isomalabaricanes to be critical for their cytotoxic activity.

Gibepyrones: α-Pyrones from Gibberella fujikuroi

Barrero, Alejandro F.,Oltra, Juan E.,Herrador, Maria M.,Cabrera, Eduardo,Sanchez, Juan F.,et al.

, p. 141 - 150 (2007/10/02)

Six α-pyrones, called gibepyrones A-F, were identified in three different culture media of G. fujikuroi (IMI 58289).Their structures were determined using both spectroscopic techniques and chemical synthesis.Their antimicrobial activity has been screened.

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