14648-22-7

Basic information

• Product Name: N-[2-(3,4-dimethoxyphenyl)ethyl]-3-(2,5-dioxopyrrolidin-1-yl)propanamide
• CAS NO: 14648-22-7
• Molecular Formula: C₁₇H₂₂N₂O₅
• Molecular Weight: 334.367
• Mol File: 14648-22-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 603.4°C at 760 mmHg
• Flash Point: 318.7°C
• Density: 1.218g/cm³
• Vapor Pressure: 1.63E-14mmHg at 25°C
• Refractive Index: 1.546
• CAS DataBase Reference: N-[2-(3,4-dimethoxyphenyl)ethyl]-3-(2,5-dioxopyrrolidin-1-yl)propanamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[2-(3,4-dimethoxyphenyl)ethyl]-3-(2,5-dioxopyrrolidin-1-yl)propanamide(14648-22-7)
• EPA Substance Registry System: N-[2-(3,4-dimethoxyphenyl)ethyl]-3-(2,5-dioxopyrrolidin-1-yl)propanamide(14648-22-7)

Safety Data

• Hazardous Substances Data: 14648-22-7(Hazardous Substances Data)

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Relevant articles and documents

Diazaestrones and analogs. I. Pharmacological study and synthesis of heterosteroid analogs to establish structure-analgesic activity relationships

With the intention of showing the effect, about pharmacological properties, in replacing two estron asymetric carbon by nitrogen atoms and removal of angular methyl from steroid, stereospecific synthesis of 8,13-diazaestron and several substituted similar compounds was realized from β-1-(succinimidoethyl)-dihydroisoquinolines, precursors of a C open ring synthesis. The splitting of the 2-methoxydiazaestron methyl ester was carried out by mean of binaphthylphosphoric acid, and synthesis of several modified analogs of heterosteroid, was carried out to determine the effect of aromatic ring reduction, lactamic carbonyl reduction, and distance between 8 and 13 nitrogen atoms, about pharmacological activity. Hormonal, spasmolytic and analgesic activities were studied, good results were observed in analgesic activity.