146490-96-2Relevant academic research and scientific papers
Synthesis of inositol phospholipids with thiophosphoester bonds
Alisi,Brufani,Filocamo,Gostoli,Maiorana,Cesta,Ferrari,Lappa,Pagella
, p. 7793 - 7796 (2007/10/02)
The synthesis of phosphatidylinositol (PI) analogues (±)1-O-(1-O-octadecanoyl-2-O-acetyl-rac-3-thioglycerylphosphoryl)-myo -inositol(7), (±)1-O-(1,2-di-O-octadecyl-rac-3-thioglycerylphosphoryl)-myo-inositol (14a), (±)1-O-(1,2-di-O-octyl-rac-3-thioglycerylphosphoryl)-myo-inositol(14b ) and (±)1-O-(1-O-octadecyl-2-O-methyl-rac-3-thioglycerylphosphoryl)-myo-in ositol(14c) designed to show a novel mode of PI-phospholipase C (PI-PLC) inhibition, is described.
