146498-76-2

Upstream product

• 1192-62-7 1-(2-furyl)-1-ethanone 
• 2216-94-6 phenylpropynoic acid ethyl ester 

Downstream Products

• 25551-92-2 2-(α-furyl)-6-phenyl-4H-pyran-4-one 
• 146498-83-1 5-hydroxy-5-<β-hydroxyimino-β-(α-furyl)ethyl>-3-phenyl-4,5-dihydroisoxazole 

Relevant academic research and scientific papers

Synthesis of 5-substituted-1-phenylpent-1-yne-3,5-diones and its derivatives

The title compounds acetylenic β-diketones (4) have been synthesized by the condensation of ethyl phenylpropiolate (1) with ketones 2a, b in the presence of sodium ethoxide, and converted into the corresponding 4H-pyran-4-ones (5a, b) and 3(2H)-furanone (6a) derivatives. 2-Pyrazoline (8a) and 5-pyridazinol (9a), 2-isoxazoline (10a) and isoxazole (11a), and 6-thiathiophthene (12a) derivatives have also been prepared from 5-(α-furyl)-1-phenylpent-1-yne-3,5-dione (4a) by treatment with hydrazine hydrate, hydroxylamine, and phosphorus pentasulphide, respectively.Thestructures of all the compounds have been established by their elemental analyses and spectral data.