146579-22-8Relevant academic research and scientific papers
Preparation and biological activity of 6-benzylaminopurine derivatives in plants and human cancer cells
Dolezal, Karel,Popa, Igor,Krystof, Vladimir,Spichal, Lukas,Fojtikova, Martina,Holub, Jan,Lenobel, Rene,Schmuelling, Thomas,Strnad, Miroslav
, p. 875 - 884 (2007/10/03)
To study the structure-activity relationships of aromatic cytokinins, the cytokinin activity at both the receptor and cellular levels, as well as CDK inhibitory and anticancer properties of 38 6-benzylaminopurine (BAP) derivatives were compared in various
Spezific Interaction of Cytokinins and Their Analogs with Rotenone-sensitive Internal NADH Dehydrogenase in Potato Tuber Mitochondria
Sue, Masayuki,Miyoshi, Hideto,Iwamura, Hajime
, p. 1806 - 1809 (2007/10/03)
Effects of cytokinins were studied on rotenone-sensitive NADH dehydrogenase in mitochondria from fresh potato tubers (Solanum tuberosum), in consideration of the operation of external and rotenone-insensitive internal NADH dehydrogenases that has not been
Purine cytokinines in the synthesis of 2',3'-dideoxynucleosides
Hjuler-Nielsen, H. P.,Motawia, M. S.,Pedersen, E. B.,Nielsen, C.
, p. 523 - 528 (2007/10/02)
A series of 2',3'-unsaturated and 2',3'-dideoxynucleoside analogues of cytokinines have been synthesized and evaluated for their inhibitory activity against human immunodeficiency virus (HIV) in MT-4 cells. 2,3-Dideoxy sugar derivatives were coupled with the purine bases 3 according to the Friedel-Crafts catalyzed silyl Hilbert Johnson method to yield anomeric mixtures of the nucleosides 8 and 12 in 15-44percent yield.The mixtures were reacted with tetrabutylammonium fluoride (TBAF) and column chromatography separated the anomers of the desired nucleosides 9b-e, 10b-e, 13 and 14.Reverse HPLC was applied to the compounds to remove contamination by TBAF.Key Words: glycosidation / cytokinines / 2',3'-dideoxynucleosides / HIV
