146601-29-8Relevant articles and documents
A Novel Nucleoside Phosphoramidite Synthon Derived from 1R,2S-Ephedrine
Iyer, Radhakrishnan P.,Yu, Dong,Ho, Nan-Hui,Tan, Weitian,Agrawal, Sudhir
, p. 1051 - 1054 (2007/10/02)
The stereoselective synthesis of the nucleoside phosphoramidite 6 by reaction of the chiral oxazaphospholidine 4 with 5'-DMT-T is reported.The novel phosphoramidite synthon, 6, is stereoselectively converted to 8 by oxidative sulfurization with 1.The oxaz
A SIMPLE AND CONVENIENT SYNTHESIS OF 2-PHOSPHONOMETHYL PYRIDINES
Page, Patrick,Mazieres, Marie-Rose,Bellan, Jacques,Sanchez, Michel
, p. 205 - 210 (2007/10/02)
The Michaelis-Becker-Nylen reaction is well suited for the synthesis of 2-phosphonomethyl pyridines.We have improved this four steps method in a one pot reaction using commercial reagents.By this general procedure we have prepared seven new 2-phosphonomethyl pyridines (Ia-g) under mild conditions with higher yields.Key words: 2-phosphono pyridines; 2-phosphonomethyl pyridines; Michaelis-Becker-Nylen reaction; new phosphonates; potential ligands.