146611-79-2

Basic information

• Product Name: 6,6'-Bis-[bis-(4-methoxy-phenyl)-phosphinoyl]-3,3'-dimethoxy-2,4,2',4'-tetramethyl-biphenyl
• CAS NO: 146611-79-2
• Molecular Weight: 790.83
• Mol File: 146611-79-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6,6'-Bis-[bis-(4-methoxy-phenyl)-phosphinoyl]-3,3'-dimethoxy-2,4,2',4'-tetramethyl-biphenyl(CAS DataBase Reference)
• NIST Chemistry Reference: 6,6'-Bis-[bis-(4-methoxy-phenyl)-phosphinoyl]-3,3'-dimethoxy-2,4,2',4'-tetramethyl-biphenyl(146611-79-2)
• EPA Substance Registry System: 6,6'-Bis-[bis-(4-methoxy-phenyl)-phosphinoyl]-3,3'-dimethoxy-2,4,2',4'-tetramethyl-biphenyl(146611-79-2)

Safety Data

• Hazardous Substances Data: 146611-79-2(Hazardous Substances Data)

Upstream product

• 135630-64-7 3,3'-dimethoxy-2,2',4,4'-tetramethyl-1,1'-biphenyl 
• 135630-62-5 3-iodo-2,6-dimethylaniline hydrochloride 
• 135630-63-6 3-iodo-2,6-dimethylphenyl methyl ether 
• 81-20-9 2,6-dimethylnitrobenzene 
• 56404-21-8 1-iodo-2,4-dimethyl-3-nitro-benzene 

Downstream Products

• 135630-68-1 (R)-p-MeO-BIMOP 

Relevant articles and documents

Synthesis of axially dissymmetric biphenylbisphosphine ligands, BIMOPs and asymmetric hydrogenations of β-keto ester and α,β-unsaturated carboxylic acid catalyzed by their ruthenium (II) complexes

Axially dissymmetric biphenylbisphosphine ligands, BIMOP (1a) and p-MeO-BIMOP (1b) have been newly designed and prepared. The ruthenium (II) complexes of (R)-1a and 1b proved to be excellent catalysts in asymmetric hydrogenations of methyl 3-oxobutanoate and tiglic acid affording (R)-methyl 3-hydroxybutanoate of 95-99 % ee and (R)-2-methylbutyric acid of 86-91 % ee, respectively.