146679-13-2Relevant academic research and scientific papers
Synthesis of 1-amino-2,2-dialkylcyclopropanecarboxylic acids via base-induced cyclization of γ-chloro-α-imino ester
Boeykens,De Kimpe,Abbaspour Tehrani
, p. 6973 - 6985 (2007/10/02)
β-Chloro ketones were oxidatively transformed into α-keto carboxylic esters and condensed with primary amines in the presence of titanium(IV) chloride. Base-induced cyclization of the resulting γ-chloro-α-imino esters, incorporating suitable N-substituent
