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146714-63-8

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146714-63-8 Usage

Chemical Properties

Light Brown Solid

Uses

4-(2-Methoxyphenyl)-N-2-pyridinyl-1-piperazineacetamide is used in the preparation of WAY 100635 (W49865), a dopamine D4 receptor.

Check Digit Verification of cas no

The CAS Registry Mumber 146714-63-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,6,7,1 and 4 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 146714-63:
(8*1)+(7*4)+(6*6)+(5*7)+(4*1)+(3*4)+(2*6)+(1*3)=138
138 % 10 = 8
So 146714-63-8 is a valid CAS Registry Number.

146714-63-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-(2-Methoxyphenyl)-N-2-pyridinyl-1-piperazineacetamide

1.2 Other means of identification

Product number -
Other names 2-[4-(2-methoxyphenyl)piperazin-1-yl]-N-pyridin-2-ylacetamide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:146714-63-8 SDS

146714-63-8Downstream Products

146714-63-8Relevant articles and documents

Synthesis and evaluation of 4-(2'-methoxyphenyl)-1-[2'-[N-(2''- pyridinyl)-p-iodobenzamido]ethyl]piperazine (p-MPPI): A new iodinated 5- HT(1A) ligand [2]

Zhuang,Kung,Kung

, p. 1406 - 1407 (1994)

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Structural Insights into 5-HT1A/D4 Selectivity of WAY-100635 Analogues: Molecular Modeling, Synthesis, and in Vitro Binding

Dilly, Sébastien,Liégeois, Jean-Fran?ois

, p. 1324 - 1331 (2016/08/02)

The resurgence of interest in 5-HT1A receptors as a therapeutic target requires the existence of highly selective 5-HT1A ligands. To date, WAY-100635 has been the prototypical antagonist of these receptors. However, this compound als

NOVEL SYNTHESIS METHOD

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Page/Page column 17, (2013/04/10)

The present invention relates to a method of making compounds having affinity for the 1 A subtype of the serotonin receptor, i.e. 5HT1A. The method of the present invention provides advantages over the known methods of synthesis. The compounds

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