146724-84-7

Basic information

• Product Name: NOC-7
• Synonyms: 3-(2-HYDROXY-1-METHYL-2-NITROSOHYDRAZINO)-N-METHYL-1-PROPANAMINE;1-HYDROXY-2-OXO-3-(N-METHYLAMINOPROPYL)3-METHYL-1-TRIAZENE;1-HYDROXY-2-OXO-3-(N-3-METHYL-AMINOPROPYL)-3-METHYL-1-TRIAZENE;NOC-7;1-hydroxy-3-methyl-3-(methyl-*aminopropyl)-2-oxo-;3-(2-Hydroxy-1-methyl-2-nitrosohydrazino)-N-methylpropylamine;1-Hydroxy-2-oxo-3-(N-methyl-3-aminoethyl)-3-methyl-1-triazene;3-(2-Hydroxy
• CAS NO: 146724-84-7
• Molecular Formula: C5H14N4O2
• Molecular Weight: 162.19
• Product Categories: Nitric Oxide Reagents
• Mol File: 146724-84-7.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 250.4°Cat760mmHg
• Flash Point: 105.3°C
• Appearance: /
• Density: 1.18g/cm³
• Vapor Pressure: 0.00343mmHg at 25°C
• Refractive Index: 1.51
• Storage Temp.: -20C
• Solubility: Water
• PKA: 0.18±0.69(Predicted)
• Stability: Store at -20°C, Light and Moisture Sensitive
• CAS DataBase Reference: NOC-7(CAS DataBase Reference)
• NIST Chemistry Reference: NOC-7(146724-84-7)
• EPA Substance Registry System: NOC-7(146724-84-7)

Safety Data

• Hazardous Substances Data: 146724-84-7(Hazardous Substances Data)

Usage

Description

NOC-7, also known as a stable NO-amine complex, is a chemical compound that can spontaneously release nitric oxide (NO) under physiological conditions. It is characterized by its white powder form and has a half-life of NO release of 5 minutes in 0.1 M PBS at pH 7.4 and 37°C.

Uses

Used in Pharmaceutical Industry:
NOC-7 is used as a NO donor for various therapeutic applications due to its ability to release nitric oxide spontaneously under physiological conditions. This property makes it a promising candidate for the development of drugs targeting conditions that can benefit from increased nitric oxide levels, such as cardiovascular diseases, erectile dysfunction, and certain types of cancer.
Used in Research Applications:
In the field of scientific research, NOC-7 is utilized as a tool to study the effects of nitric oxide on various biological processes. Its controlled release of NO allows researchers to investigate the role of nitric oxide in cellular signaling, immune response, and other physiological functions.
Used in Drug Delivery Systems:
NOC-7 can be incorporated into drug delivery systems to enhance the therapeutic effects of nitric oxide. By encapsulating or conjugating NOC-7 with other drugs or carriers, it is possible to improve the targeted delivery of nitric oxide to specific tissues or cells, thereby increasing its efficacy and reducing potential side effects.
Overall, NOC-7 is a versatile compound with potential applications in various industries, particularly in the development of novel therapeutics and research tools for understanding the role of nitric oxide in biological systems.

InChI:InChI=1/C5H14N4O2/c1-6-4-3-5-8(2)9(11)7-10/h6,11H,3-5H2,1-2H3