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NOC-12 is a stable NO-amine complex that can spontaneously release nitric oxide (NO) under physiological conditions. It is a white powder with a half-life of NO release of 100 minutes in 0.1 M PBS at pH 7.4 and 37°C.

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  • 146724-89-2 Structure
  • Basic information

    1. Product Name: NOC-12
    2. Synonyms: N-ETHYL-2-(1-ETHYL-2-HYDROXY-2-NITROSOHYDRAZINO) ETHANAMINE;NOC-12;1-HYDROXY-2-OXO-3-(N-ETHYL-2-AMINOETHYL)-3-ETHYL-1-TRIAZENE;3-ETHYL-3-(ETHYLAMINOETHYL)-1-HYDROXY-2-OXO-1-TRIAZENE;3-ETHYL-3-(ETHYLAMINOETHYL)-1-HYDROXY-*2 -OXO-1-TRIA;N-Ethyl-2-(1-ethyl-2-hydroxy-2-nitrosohydrazino)-ethylamine;1-Hydroxy-2-oxo-3-(N-ethyl-3-aminoethyl)-3-ethyl-1-triazene;N-Ethyl-2-(1-ethyl-2
    3. CAS NO:146724-89-2
    4. Molecular Formula: C6H16N4O2
    5. Molecular Weight: 176.22
    6. EINECS: N/A
    7. Product Categories: Nitric Oxide Reagents
    8. Mol File: 146724-89-2.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 264.6°C at 760 mmHg
    3. Flash Point: 113.8°C
    4. Appearance: /
    5. Density: 1.15g/cm3
    6. Vapor Pressure: 0.00134mmHg at 25°C
    7. Refractive Index: 1.507
    8. Storage Temp.: −20°C
    9. Solubility: Water
    10. Stability: Store at -20°C, Light and Moisture Sensitive
    11. CAS DataBase Reference: NOC-12(CAS DataBase Reference)
    12. NIST Chemistry Reference: NOC-12(146724-89-2)
    13. EPA Substance Registry System: NOC-12(146724-89-2)
  • Safety Data

    1. Hazard Codes: Xi
    2. Statements: 36/37/38
    3. Safety Statements: 26-36
    4. WGK Germany: 3
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 146724-89-2(Hazardous Substances Data)

146724-89-2 Usage

Uses

Used in Pharmaceutical Industry:
NOC-12 is used as a nitric oxide donor for its ability to release NO spontaneously under physiological conditions. This property makes it a potential candidate for various therapeutic applications, such as vasodilation, anti-inflammatory effects, and immune response modulation.
Used in Research Applications:
In the field of scientific research, NOC-12 is used as a tool to study the role of nitric oxide in various biological processes. Its controlled release of NO allows researchers to investigate the effects of nitric oxide on cellular signaling, gene expression, and other physiological responses.
Used in Drug Delivery Systems:
NOC-12 can be incorporated into drug delivery systems to enhance the therapeutic effects of nitric oxide. By using NOC-12 as a NO donor, researchers can develop novel drug formulations that provide targeted and controlled release of nitric oxide, potentially improving the efficacy and safety of various treatments.
Used in Anticancer Applications:
Although not explicitly mentioned in the provided materials, nitric oxide has been shown to have potential applications in cancer therapy. NOC-12, as a stable NO donor, could be explored for its potential use in cancer treatment, particularly in combination with other anticancer agents to enhance their effects and overcome drug resistance.

Check Digit Verification of cas no

The CAS Registry Mumber 146724-89-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,6,7,2 and 4 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 146724-89:
(8*1)+(7*4)+(6*6)+(5*7)+(4*2)+(3*4)+(2*8)+(1*9)=152
152 % 10 = 2
So 146724-89-2 is a valid CAS Registry Number.
InChI:InChI=1/C6H16N4O2/c1-3-7-5-6-9(4-2)10(12)8-11/h7,12H,3-6H2,1-2H3

146724-89-2 Well-known Company Product Price

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  • Sigma

  • (E3145)  3-Ethyl-3-(ethylaminoethyl)-1-hydroxy-2-oxo-1-triazene  ≥90%

  • 146724-89-2

  • E3145-10MG

  • 1,904.76CNY

  • Detail

146724-89-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name N-Ethyl-2-(1-Ethyl-2-Hydroxy-2-Nitrosohydrazino) Ethanamine Discontinued

1.2 Other means of identification

Product number -
Other names 3-Ethyl-3-(ethylaminoethyl)-1-hydroxy-2-oxo-1-triazene

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:146724-89-2 SDS

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