1467641-79-7

Basic information

• Product Name: C₂₈H₄₄N₃O₈P
• CAS NO: 1467641-79-7
• Molecular Weight: 581.646
• Mol File: 1467641-79-7.mol

Chemical Properties

• CAS DataBase Reference: C₂₈H₄₄N₃O₈P(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₈H₄₄N₃O₈P(1467641-79-7)
• EPA Substance Registry System: C₂₈H₄₄N₃O₈P(1467641-79-7)

Safety Data

• Hazardous Substances Data: 1467641-79-7(Hazardous Substances Data)

Upstream product

• 1416992-27-2 C₂₄H₃₅N₃O₅ 
• 1416992-20-5 C₂₅H₃₅N₃O₆ 
• 25341-42-8 (S)-2-benzyloxycarbonylamino-3-cyclohexylpropionic acid 
• 113828-93-6 (S)-2-Benzyloxycarbonylamino-3-cyclohexyl-propionic acid methyl ester 
• 17193-39-4 methyl 3-cyclohexyl-L-alaninate hydrochloride 

Relevant articles and documents

Potent inhibition of norovirus by dipeptidyl α-hydroxyphosphonate transition state mimics

The design, synthesis, and evaluation of a series of dipeptidyl α-hydroxyphosphonates is reported. The synthesized compounds displayed high anti-norovirus activity in a cell-based replicon system, as well as high enzyme selectivity.

MACROCYCLIC AND PEPTIDOMIMETIC COMPOUNDS AS BROAD-SPECTRUM ANTIVIRALS AGAINST 3C OR 3C-LIKE PROTEASES OF PICORNAVIRUSES, CALICIVIRUSES AND CORONAVIRUSES

Antiviral protease inhibitors, including macrocylic transition state inhibitors and peptidomimetics are disclosed, along with related antiviral compounds, and methods of using the same to treat or prevent viral infection and disease. The compounds possess broad-spectrum activity against viruses that belong to the picornavirus-like supercluster, which include important human and animal pathogens including noroviruses, sapoviruses, enteroviruses, poliovirus, foot-and-mouth disease virus, hepatitis A virus, human rhinovirus (cause of common cold), human coronavirus (another cause of common cold), transmissible gastroenteritis virus, murine hepatitis virus, feline infectious peritonitis virus, and severe acute respiratory syndrome coronavirus.