146765-74-4Relevant academic research and scientific papers
Macrolactonization of Alkynyl Alcohol through Rh(I)/Yb(III) Catalysis
Zhang, Wen-Wen,Gao, Tao-Tao,Xu, Li-Jin,Li, Bi-Jie
, p. 6534 - 6538 (2018)
A catalytic macrolactonization through oxidative cyclization of alkynyl alcohol by synergistic transition-metal and Lewis-acid catalysis was developed. Because the alkynyl alcohol substrates involved in this method are different from the seco acids that are used in conventional macrolactonization methods, the current method provides a strategically distinct entry to macrolactones. In addition to the operational simplicity, this macrolactonization protocol proceeds at relatively high concentration, precluding the need for high dilution or slow addition procedures.
Pyryliumolates. III. Synthesis of Annulated Benzotropolones
Plueg, Carsten,Friedrichsen, Willy,Debaerdemaeker, Tony
, p. 205 - 216 (2007/10/03)
Dirhodiumtetraacetate catalyzed nitrogen extrusion from diazocarbonyl compounds (2a-f, 19c, 23d-f, 25b) yields benzopyryliumolates (3), which were trapped intramolecularly in situ to give tetracyclic adducts (4a, 5a-d, 20, 24a-c, 26). Starting with 5a and 5d annulated benzotropolones (12a, d) are accessible.
Pyryliumolates. 1. A simple access to anellated benzotropolones
Plug,Friedrichsen
, p. 7509 - 7510 (2007/10/02)
The synthesis of benzotropolones 4a,b utilizing an intramolecular 1,3-dipolar cycloaddition reaction with benzopyryliumolates (2a,b; generated in situ) is reported.
