1468-26-4

Basic information

• Product Name: 8-AZAXANTHIN
• Synonyms: 1h-v-triazolo(4,5-d)pyrimidine-5,7(4h,6h)-dione;2,6-dioxy-8-azapurine;nsc756;usafcb-26;v-triazolo(4,5-d)pyrimidine-5,7-diol;AZAXANTHIN,8;8-AZAXANTHIN;8-AZAXANTHINE
• CAS NO: 1468-26-4
• Molecular Formula: C₄H₃N₅O₂
• Molecular Weight: 153.1
• EINECS: 215-992-2
• Product Categories: Nucleotides and Nucleosides;5-FOA;Bases & Related Reagents;Nucleotides
• Mol File: 1468-26-4.mol
• Article Data: 2

Chemical Properties

• Melting Point: >230°C
• Boiling Point: 275.98°C (rough estimate)
• Appearance: /
• Density: 1.6725 (rough estimate)
• Refractive Index: 1.8000 (estimate)
• BRN: 10424
• CAS DataBase Reference: 8-AZAXANTHIN(CAS DataBase Reference)
• NIST Chemistry Reference: 8-AZAXANTHIN(1468-26-4)
• EPA Substance Registry System: 8-AZAXANTHIN(1468-26-4)

Safety Data

• Safety Statements: 24/25
• WGK Germany: 3
• RTECS: XZ5950000
• F: 10-23
• Hazardous Substances Data: 1468-26-4(Hazardous Substances Data)

Usage

Chemical Properties

Light Yellow Powder

InChI:InChI=1/C4H3N5O2/c10-3-1-2(8-9-7-1)5-4(11)6-3/h1H,(H2,5,6,7,8,10,11)

Upstream product

• 134-58-7 8-azaguanine 
• 1004-76-8 5,6-diamino-2-thioxo-2,3-dihydropyrimidin-4(1H)-one 
• 7697-37-2 nitric acid 
• 57-13-6 urea 
• 42965-55-9 5,6-diaminouracil sulfate 
• 31571-52-5 5-thioxo-1,4,5,6-tetrahydro-[1,2,3]triazolo[4,5-d]pyrimidin-7-one 
• 79-11-8 chloroacetic acid 
• 4342-07-8 5-amino-1,2,3-triazole-4-carboxamide 

Downstream Products

• 4342-07-8 5-amino-1,2,3-triazole-4-carboxamide 
• 20420-84-2 4-Amino-1,2,3-triazol-5-carbonsaeure 
• 4730-45-4 8-Aza-xanthosin 
• 79687-55-1 7,9-dimethyl-8-azaxanthinium benzenesulfonate 
• 117740-59-7 1-n-propyl-3-phenyl-7-(2-morpholinoethyl)-8-azaxanthine 

Relevant articles and documents

Preparation method of ticagrelor impurities

The invention belongs to the field of chemical synthesis and particularly relates to a preparation method of ticagrelor impurities. The preparation method is a brand-new synthesis route and mainly comprises the five steps of exocondensation, substitution, isopropylidene removal and the like, wherein urea which is low in price and easy to obtain is used as a raw material for a reaction under a mildcondition in combination with a condensing agent composition, an alkaline reagent and the like. According to the preparation method, the product conversion rate and yield are high, the purity of 98%can be reached even without column chromatography purification, operation is easy, the preparation method is suitable for large-scale industrial production of ticagrelor impurity compounds VIII, and detection and monitoring of the impurities in the ticagrelor synthesis process are benefited.